700 Easy Diagnostic Method for Macro-Ast
نویسندگان
چکیده
منابع مشابه
Macro-AST in an asymptomatic young patient.
Elevated enzyme activities in plasma may sometimes be due to the presence of macroenzymes.1,2 Macroenzymes are high molecular mass complexes of plasma enzymes with immunoglobulins (IgG, IgA or IgM) or other plasma components with reduced plasma clearance and prolonged half life, resulting in elevated serum activities due to the “trapping” of the enzymes in serum.3 These results may thus be erro...
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BACKGROUND MCAD-deficiency is the most common inborn error of fatty acid oxidation now included in many newborn screening programms using MS/MS. During prolonged catabolic episodes, patients may suffer from metabolic decompensation with dysfunction of liver, skeletal- and heart muscle as well as brain. In anabolism, neither clinical symptoms nor biochemical signs of organ dysfunction occur. C...
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Macro-aspartate transaminase (macro-AST) must be considered when the aspartate transaminase (AST) level is chronically high without any liver, cardiac, or muscle disease. Many specialized laboratory techniques have been recommended for diagnosing macro-AST, including the polyethylene glycol immune precipitate technique, which is simple. This study presents a considerably easier method based on ...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 2012
ISSN: 0003-9888,1468-2044
DOI: 10.1136/archdischild-2012-302724.0700